Hyaluronidases 溶解酶
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- Hyaluronidases 溶解酶
别名
玻尿酸溶解酶
项目介绍
溶解酶,是一种能水解玻尿酸的酶,能将注射入人体内的玻尿酸溶解的物质,主要用来修复玻尿酸塑形失败,比如说玻尿酸填充后,效果不满意或者操作不当引起的失败现象出现,就可以用溶解酶把玻尿酸给溶了,堪称是微整界的后悔药。
项目特色
玻尿酸的“解药”,可以矫正玻尿酸填充过度过量后的不完美效果。
适合人群
对注射后效果不满意者; 玻尿酸填充过度过量后的不完美效果者; 想在玻尿酸注射区域,填充其他物质者(如自体脂肪)
关注度
⭐⭐⭐⭐⭐
安全度
⭐⭐⭐⭐✩
复杂度
⭐✩✩✩✩
项目优点
用于矫正玻尿酸过度过量充填的不完美效果,堪称是微整界的后悔药.
项目缺点
过量注射可导致局部水肿。
禁忌人群
注射过肉毒素的部位48小时内,不能注射溶解酶,因为溶解酶会促使肉毒素严重扩散; 急慢性病,还有正在口服一些药物,尤其是有过敏史者; 孕妇或哺乳期者。
留疤
无
治疗时长
10-20 分钟
麻醉方式
无需麻醉或表麻
治疗周期
单次
操作方式
注射
效果持续
持久
恢复时间
1-3天
操作人员资质
医疗美容科或整形科执业医师
疼痛感
轻度疼痛
术前必读
- 当天不要化妆,保持面部清洁;
- 女性避开月经期,以免加重淤青和肿胀;妊娠期、哺乳期女性需要提前告知医生;
- 注射前禁用抗凝血药物(阿司匹林、维生素E);
- 检查身体健康情况,无严重器官疾病、无出凝血疾病、无糖尿病及免疫性疾病及神经运动功能障碍;
- 注射部位无感染病灶、无炎症(例如痤疮、皮疹等)。
0-第3天
轻微肿胀期 恢复提示:
注射区域,会有轻微发红、淤青等现象出现,为正常现象。
护理方法:
- 注射后6小时内,避免接触注射区域;
- 注射当天针眼勿沾水、洗脸勿用过热的水;
- 注射第2天,轻轻按摩注射区域,以促进药物均匀溶解;
4-第7天
效果显现期 恢复提示:
效果显现,注射区域的玻尿酸被溶解掉。
护理方法:
- 一周内禁食海鲜、辛辣等刺激性食物
8-第180天
效果稳定期 恢复提示:
若注射区域玻尿酸未完全溶解掉,可以待半个月至一个月后,进行再次溶解。
护理方法:
- 如有任何不适,请及时到院复诊
温馨提醒
以上术后护理仅供参考。因个体差异、采用术式不同,恢复周期、拆线时间及护理方法均会有所不同。具体护理方案,建议遵医嘱执行。
Alias Name
Lysozyme
Procedure Detail
Hyaluronidase is an enzyme (compounded by special pharmacies) that causes hydrolysis (breakdown) of hyaluronic acid. It is often referred to as a reversal agent for hyaluronic acid-based fillers. Hyaluronidase is used to dissolve hyaluronic acid fillers that have been placed incorrectly, excessively, or unevenly. It is injected into the same locations that the filler already is.
Features
HA filler antidote, it can correct or improve the results of filler treatment.
Suitable Candidate
Those who are dissatisfied with HA injection result; those who received improper amount of hyaluronic acid filler; those who want to fill other substances (such as autologous fat) in the same area.
Popularity
⭐⭐⭐⭐⭐
Safety
⭐⭐⭐⭐✩
Complexity
⭐✩✩✩✩
Pros
An antidote known to correct or make adjustment to HA filler.
Cons
Might cause bruising and water retention.
Unsuitable Candidate
Within 48 hours of the injection of botulinum toxin, lysozyme cannot be injected, because lysozyme will promote spreading of botulinum toxin; acute and chronic diseases, and those on oral medications, especially those with a history of allergies; pregnant or breastfeeding.
Scar
No
Treatment Time
10-20 min
Anesthesia Method
No anesthesia or epi-anesthesia
Treatment Course
1 time
Procedures Technique
Injection
Sustainability
Permanent
Recovery Period
1-3 days
Qualification
Practitioner in medical aesthetics or plastic surgeon
Pain Scale
Mild
Before the Procedure
- Do not apply makeup on that day and keep your face clean.
- Avoid treatment during menstrual period to prevent bruising and swelling; women in pregnancy and lactation need to inform the doctor in advance.
- Stop taking anticoagulant drugs (aspirin, vitamin E) before injection.
- Know your body, no serious organ diseases, no coagulation diseases, no diabetes and immune diseases and neuromotor dysfunction.
- No infection and inflammation at the injection site (such as acne, rash, etc.).
0-3rd days
Reminder of the slight swelling period from 0 to 3 days:
The injection area, there will be slight redness, bruising and other phenomena, which is normal.
After care methods:
- Avoid contact with the injection area within 6 hours.
- Don’t get wet on the injection site and wash your face with hot water on the same day.
- On the second day of injection, gently massage the injection area to promote uniform dissolution.
4-6th days
4 days to 7 days of development period Recovery tips:
The effect will show at this time, and the hyaluronic acid in the injection area is dissolved.
After care:
- Don’t eat seafood and spicy food for a week.
8-180th days
8 to 15 days ~ stabilization period Recovery tips:
If the hyaluronic acid in the injection area is not completely dissolved, wait for 2 weeks to one month before another clinic visit.
After care methods:
- If there is any discomfort, please go to the hospital for follow-up consultation.
Reminder
The above postoperative care is for reference only. Due to individual differences and different surgical procedures, the recovery cycle, suture removal time and aftercare methods will be different. The specific plan is to follow the doctor’s advice.
FAQ 常见问答题
It is generally safe to take a week apart; if there is an emergency, it is at least 72 hours apart. This is related to the product absorption.
一般间隔一周比较稳妥;如果紧急的情况,就间隔72小时,这个和药物吸收情况有关.
Before the treatment, a pre allergy patch test should be carried out; the skin test method is: taking 0.02ml of 150u/ml concentration of the solution, if a rash with pseudopods appeared within 5 minutes and last for 20-30 minutes, and itching, it is allergy positive; but erythema appears locally due to vasodilation, it is not allergic.
使用溶解酶之前,需要进行使用前的过敏测试,也就是溶解酶皮试;其皮试方法为:取150u/ml浓度的药液0.02ml皮内注射,如5分钟内出现具有伪足的疹块,持续20-30分钟,并有瘙痒感,示为阳性;但在局部出现一次性红斑,是由于血管扩张所引起,则并非为阳性。
As long as regular operation is carried out, there should be no side effects; however, if the treatment was overdose and excessive injection can cause local edema, allergies manifest as erythema, nausea, vomiting, dizziness, rapid heartbeat, and blood pressure drop; Patient should receive proper treatment as soon as possible with epinephrine, corticosteroids and antihistamines.
只要正规操作,一般不会有副作用的出现;但若由于操作不当,导致药物过量;过量注射可导致局部水肿,过敏表现为红斑、恶心、呕吐、头晕、心跳加速和血压下降等;应及时停药,并采用支持疗法,急救可用肾上腺素、皮质激素和抗组织胺药等.
The most difficult aspect of using hyaluronidase is judging the amount required to dissolve a certain amount of filler. Generally speaking, one solubilizing enzyme (1500IU) + 3ml sodium chloride for injection → divided into 10 bottles → can dissolve 10ml of hyaluronic acid. However, it is still varied on each situation.
一般来说,一支溶解酶(1500IU)+3ml注射用氯化钠→分成10支→可以溶解10ml的玻尿酸;但具体注射多少溶解酶的量,需按照注射玻尿酸的量,来进行注射。
If the result is not good or unsatisfying, it can be dissolved with hyaluronidase within 48 hours, and then it can be filled with hyaluronic acid again.
在玻尿酸注射后感觉效果不太好,可以在48小时内,用溶解酶进行溶解,之后可再次用玻尿酸进行填充。